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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITX2
All Species:
32.42
Human Site:
S186
Identified Species:
79.26
UniProt:
Q99697
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99697
NP_000316.2
317
35370
S186
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090922
317
35287
S186
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Dog
Lupus familis
XP_863661
317
35334
S186
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P97474
317
35302
S186
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Rat
Rattus norvegicus
Q9R0W1
324
35740
S193
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93385
333
36539
S202
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Frog
Xenopus laevis
Q9PWR3
326
36321
S195
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Zebra Danio
Brachydanio rerio
Q9W5Z2
314
35169
S183
W
A
A
K
G
L
T
S
A
S
L
S
T
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18400
509
53198
P366
Y
N
N
W
T
K
V
P
S
P
L
G
T
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52906
323
36184
T186
G
Q
G
T
T
K
V
T
A
Q
S
L
D
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
99
N.A.
98.7
81.1
N.A.
N.A.
78.6
75.7
78.5
N.A.
30.6
N.A.
28.4
N.A.
Protein Similarity:
100
N.A.
99.3
99
N.A.
99.3
83.9
N.A.
N.A.
83.1
79.4
83.5
N.A.
40.4
N.A.
43.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
80
80
0
0
0
0
0
90
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
80
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
80
0
20
0
0
0
0
0
0
0
90
0
% K
% Leu:
0
0
0
0
0
80
0
0
0
0
90
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
80
10
80
10
80
0
0
80
% S
% Thr:
0
0
0
10
20
0
80
10
0
0
0
0
90
0
0
% T
% Val:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% V
% Trp:
80
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _